Cellomics arrayscan vti hcs reader zeiss axiovert 200m microscope fluar 5x 0. Thermo cellomics live cell chamber 100 in stock, we. The thermo scientific arrayscan xti high content analysis hca reader is able to grow with you and your research needs. It contains zeiss microscope optics and a hamamatsu orcaer cooled 12 bit grayscale ccd camera. Hca technology was pioneered by cellomics in 1996, now part of thermo fisher scientific, and has evolved and transformed over the past twoandahalf decades with the customer in mind. Measures various cellular changes reveals specificity, cytotoxicity, and bioavailability information. Arrayscan xti hca infinity configuration offers the broadest set of capabilities for the largescale study of cell biology cellomics in a single modular platform. National center for drug screening, shanghai, china business. Thermo scientific cellomics arrayscan vti hcs reader for high. This software permits users to progress development software for high through critical activities such as acquiring, developing, optimizing and scanning a live plate or. September 2009 cellomics january 2003 october 2006 cellomics. The cellomics arrayscan ii hcshigh content screening system, pn n08, includes cellomics microplate stacker pn 738170 and cellomics arrayscan ii illumination spot light scource model. Highcontent functional genomic screening to identify novel. Our mission is to enable our customers to make the world healthier, cleaner and.
Ht1080 cell image acquired using an arrayscan system and stained with. The hca platforms are modular and powered by our proprietary hcs studio quantitative analysis software. Quantifies physiological change that occurs in individual cells and measures of population response. Integrates robotic plate handling, automated fluorescent image acquisition,and complex image analysis. Cellomics arrayscan high content screening hcs is an integration of cell based assays, robotics, high resolution fluorescent microscopy, image analysis and advanced informatics. The arrayscan vti, originally manufactured by cellomics, is a modular high content screening hcs system designed for both cellular and subcellular analysis.
Please refer to the compatible bioapplication software modules section for cellomics applications that can be used with this kit and the arrayscan hcs protocol instructions for optimal assay implementation on the arrayscan hcs reader. Thermo scientific cellomics cell health profiling v4. Phosphoh2ax is quantitated using the total or average nuclear intensity. The thermo scientific cellomics arrayscan vti hcs reader is a modular high content screening instrument designed for highcapacity automated fluorescence imaging and. Simply put, the vhcs discovery toolbox offers anyone with a pc. The arrayscan is a high content imaging instrument that offers a wide set of functions for. Thermo cellomics arrayscan vti in stock, we buy sell. Cellomics arrayscan vti hcs readerhcs studio software. Hcs and the discipline of cellomics was pioneered by a once privately held company named cellomics inc.
Cells are then fixed and highthroughput immunofluorescence was performed to stain mitochondria. Dylight fluor 488 conjugates have approximate absorptionemission maxima of 494532 nm. The thermo scientific arrayscan vti hcs reader is a modular, flexible imaging platform, designed for highcapacity, automated, quantitative cellular and subcellular analysis in fixed and live cell formats. The thermo scientific cellomics arrayscan vti hcs reader is a modular high content screening instrument designed for highcapacity automated fluorescence imaging and quantitative analysis of. These images are stored on a dell 20terabyte server and analyzed with custom algorithms that are created using various cellomics imageanalysis software. Led light engine and the hcs studio software, the arrayscan vti allows the creation of. From investigative cell biology to high throughput high content screening, the arrayscan.
Refurbished cellomics arrayscan ii hcshigh content screening. Focus, thermo scientific cellomics accufocus technology. Thermo scientific arrayscan and cellinsight highcontent platforms offer. That legacy is now part of thermo fisher scientific, with hundreds of instruments in use worldwide and close to 1,000. The assay was optimized with the thermo scientific arrayscan hcs reader using the compartmental analysis bioapplication software module. Thermo scientific arrayscan xti hca infinity configuration. Arrayscan hcs reader version vti running software versions x. Hcs road currently supports 3 instrument types and software.
Cellomics, arrayscan, kineticscan, idev, and vhcs are trademarks or registered trademarks of. Used cellomics arrayscan vti 2035951 imaging system. Whether your interest is in basic cell assays or investigating complex. The instrument features optics by carl zeiss, broad whitelight source, scientific grade digital camera.
Mnsod is quantitated using cytoplasmic intensity or the increase in cytoplasmic spot intensity. Inc computer software education penn state university 1992 1993 master of science ms, geologyearth. Kit, thermo scientific arrayscan hcs reader and the multiparameter apoptosis 1 bioapplication software provide for automated plate handling, focusing, cell image acquisition, analysis, and quantification of apoptosis. Past, present, and future of high content screening and the field of cellomics article pdf available in methods in molecular biology 356. This thermo cellomics arrayscan ii hcs integrated high content screening system is used and in excellent condition. Hc imaging provides the ability to quantify essentially any physiological change that occurs in individual cells, in addition to measures of population response. Cellomics is also a trademarked term, which is often used interchan. Pdf past, present, and future of high content screening and. The arrayscan vti features include optics by carl zeiss, broad whitelight source, 12bit cooled ccd camera, controller software. This analysis is achieved by combining automated fluorescence microscopy with software. Thermo cellomics arrayscan arrayscan ii hcs in stock, we buy.
Antitumour activity of a novel coumarinchalcone hybrid is mediated through intrinsic apoptotic pathway by inducing puma and altering baxbcl2 ratio. Combining these aspects with robotics facilitates the fast and. This analysis is achieved by combining automated fluorescence microscopy with software that, via advanced informatics, conducts quantitative analysis of the images. Highcontent screening platforms designed with biologists in mind. The cellomics arrayscan vti microarray reader is a modular, flexible imaging platform, designed for highcapacity, automated, quantitative cellular and subcellular analysis in fixed and live cell formats. Arrayscan xti live high content platform from thermo fisher. It provides all levels of technical support and consultation for researchers needing imaging of cells and tissues, flow cytometry analysis of protein expression on cells or cell cycle analysis and cell sorting.
The arrayscan software identifies and measures individual. This software license agreement agreement for the target activation bioapplication software software is entered into in conjunction with the purchase of the license to the software. Cellomics idev intelligent assay interface for operating the arrayscan vti hcs reader. Today cellomics is recognized as a discipline of quantitative cell analysis that is also. Thermo cellomics arrayscan arrayscan ii hcs integrated high content screening systems. Lep ludl table with controller a lot of software, but without a pc an empty pc but can be included. Cellinsight cx5 highcontent screening hcs platform. Cellomics is the discipline of quantitative cell analysis using bioimaging methods and. We have found that 384well plates provided a screenable genomewide platform. The center will use cellomics arrayscan high content screening reader, software and reagents for drug discovery and development. Highcontent screening platforms designed with biologists. Cellomics arrayscan vti live cell module here is a cellomics arrayscan vti live cell module for sale. From highcontent assay development, through basic cell biology research to systems biology and drug discovery and toxicology, the arrayscan xti hca infinity.
Thermo cellomics arrayscan ii hcs in stock, we buy. Refurbished cellomics arrayscan ii hcshigh content. The high throughput format enables a timesaving, unbiased acquisition and analysis of cells in a. Pdf antitumour activity of a novel coumarinchalcone. Cellomics high content screeninganalysis lund university. This software license agreement agreement for the spot detector bioapplication.
In order to provide cutting edge rnai screening technologies to duke investigators, we have obtained a cellomics arrayscan vti high content hc cell based imaging system. Imaging software thermo fisher scientific, cellomics. Bioapplication software neurite outgrowth bioapplication software for use with the arrayscan hcs reader s5000071 neuronal profiling bioapplication software for use with the arrayscan hcs reader s507032v3 based on protocol for 96well plate density. Work with our experts to sustain your critical applications. Cellomics neuroscreen 1 cells thermo fisher scientific. The instrument features a broad whitelight source, scientific grade digital camera and integrated acquisition and analysis software.
Instruments highthroughput screening core facility. Arrayscan infinity hcs reader offers the broadest set of capabilities for the largescale study of cell biology cellomics in a single modular platform. Cellomics is the discipline of quantitative cell analysis using bioimaging methods and informatics with a workflow involving three major components. This thermo cellomics arrayscan ii illumination source is used and in excellent condition. A colocalization algorithm from the cellomics arrayscan v ti software was optimized to detect the degree of colocalization between gfpparkin and mitochondrial signals. The thermocellomics arrayscan hcs system is an automated system for screening arrays of fluorescently labeled cells within a microplate. Geisinger commonwealth school of medicines microscopy and flow cytometry core supports the research of investigators and their trainees. Compatible with thermo scientific hcs studio cell analysis software and thermo scientific store image and database management software compatible with the arrayscan xti hca reader dimensions spinning disk pinholes illumination software arrayscan compatibility confocal module specifications figure 3. Cellomics arrayscan vti live hcs reader biosurplus. High content screening system thermo fisher cellomics. Thermo cellomics arrayscan ii hcs in stock, we buy sell. Thermo scientific cellomics arrayscan vti hcs reader ebay. Cellinsight cx5 highcontent screening hcs platform duke. Please read the detailed list below for system specification.
We have recently updated our hcs technology with a thermofisher cx5 hcs platform to provide imagebased quantitative phenotyping in highthroughput. Image is a composite of the gfp and brightfield images made using the arrayscan vti software. Cellomics arrayscan v louisiana state university health. Cellomics arrayscan v arrayscan vti hcs reader is an automated fluorescent microscopic imaging system designed for high content screening in fixed or live cells. Hca technology was pioneered by cellomics in 1996, now part of thermo. Arrayscan ii hcs thermo cellomics arrayscan ii hcs integrated high content screening system from thermo cellomics buy today from artisan. These software also provide powerful tools to extract quantitative information from 3d data sets such as counting particles, measuring volumes and intensities, and measuring colocalization of multiple markers. It contains zeiss microscope optics and a hamamatsu orcaer cooled 12 bit grayscale ccd. Pdf high content screening for drug discovery from. It automatically acquires multiple images per well from most standard microwell plates and microscope slides. This software license agreement agreement for the target activation. The thermo cellomics arrayscan vti is a modular high content screening instrument designed for high capacity automated fluorescence imaging and quantitative analysis of fixed and live cells. Hcs studio cell analysis software store image and database management software. Arrayscan xti hca infinity configuration offers the broadest set of capabilities for the largescale study of cell biology cellomics in a single, modular platform.
However, the robotic stacker needs its firmware reinstalled by the manufacturer. Quantitative image analysis cytometry shared resources. This software license agreement agreement for the cell health profiling. All three of these components depend on sophisticated software to acquire qualitative data, quantitative data, and the management of both images and data, respectively. The cellomics arrayscan vti thermo fisher scientific is a robotic, fluorescencebased, imaging system. This software is seamlessly integrated with our data management and informatics platform, providing rapid decisions on your data. Graduates of penn state university the names, photos, skill, job, location. Thermo cellomics l721244 arrayscan ii illumination source.
Licensor represents that it has all rights necessary to grant the license herein. The cellomics arrayscan ii hcshigh content screening system, pn n08, includes cellomics microplate stacker pn 738170 and cellomics arrayscan ii illumination spot light scource model l721244. The thermo scientific cellomics arrayscan vti hcs reader is a modular, highcontent screening instrument designed for highcapacity automated fluorescence imaging and quantitative analysis of fixed and live cells. This instrument has been tested by our inhouse service technician and is ready for use.
Integrated with software and validated for performance for simple set up and customization thermo scienti. High content imaging core ottawa hospital research institute. Cellomics store software by thermo fisher scientific manufacturer thermo fisher scientific cellomics store offers an open, enterpriseready, relational database solution, for the management of data. Thermo cellomics live cell chamber 100 easy clickquotebuy today. The backgroundcorrected image is not stored or shown. The thermo scientific cellomics arrayscan vti hcs reader is a modular high content screening instrument designed for highcapacity automated fluorescence imaging and quantitative analysis of fixed and live cells. Live cell kinetic and motility experiments yield a deeper understanding of cell functions. Cellomics store software from thermo fisher scientific. From highcontent assay development, through basic cell biology research to systems biology and drug discovery and toxicology, the arrayscan. Cellomics, arrayscan, idev, and vhcs are trademarks or registered trademarks of cellomics, inc. Thermo scientific cellomics compartmental analysis v4. Use of the target activation bioapplication requires a license from cellomics, inc. Live cells were automatically counted with the cellomics arrayscan vti hcs. Cellomics will develop and market software that will allow its cellomics store and vhcs discovery toolbox tools to store and analyze data and images generated by ge healthcares in.
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